A low quote from an operator who can't produce a USDOT number isn't a deal — it's a liability risk.
Federal law requires any company operating vehicles designed to carry more than 15 passengers, including the driver, in interstate commerce to hold USDOT operating authority and meet minimum insurance requirements. Passenger carriers at that size are held to a $5 million minimum liability coverage threshold — well above standard commercial auto policies.
Beyond the paperwork, ask about the carrier's out-of-service rate and safety rating on the FMCSA's public SAFER database, and confirm drivers are subject to the same drug and alcohol testing program required of any interstate commercial driver.